Publications

2020

2019

2018


2017

2016


2015


2014


2013


2012


Prior to 2012

  • Dell'Orco D, Koch KW. A dynamic scaffolding mechanism for rhodopsin and transducin interaction in vertebrate vision. Biochem J. 2011 Dec 1;440(2):263-71. doi: 10.1042/BJ20110871. PubMed PMID: 21843151.

  • Zernii EY, Komolov KE, Permyakov SE, Kolpakova T, Dell'orco D, Poetzsch A, Knyazeva EL, Grigoriev II, Permyakov EA, Senin II, Philippov PP, Koch KW. Involvement of the recoverin C-terminal segment in recognition of the target enzyme rhodopsin kinase. Biochem J. 2011 Apr 15;435(2):441-50. doi: 10.1042/BJ20110013. PubMed PMID: 21299498.

  • Dell'Orco D, Müller M, Koch KW. Quantitative detection of conformational transitions in a calcium sensor protein by surface plasmon resonance. Chem Commun (Camb). 2010 Oct 21;46(39):7316-8. doi: 10.1039/c0cc02086a. Epub 2010 Sep 10.PubMed PMID: 20835460.

  • Dell'Orco D, Koch KW. Systems biochemistry approaches to vertebrate phototransduction: towards a molecular understanding of disease. Biochem Soc Trans. 2010 Oct;38(5):1275-80. doi: 10.1042/BST0381275. PubMed PMID: 20863298.

  • Dell'Orco D, Lundqvist M, Oslakovic C, Cedervall T, Linse S. Modeling the time evolution of the nanoparticle-protein corona in a body fluid. PLoS One. 2010 Jun 3;5(6):e10949. doi: 10.1371/journal.pone.0010949. PubMed PMID: 20532175; PubMed Central PMCID: PMC2880601.

  • Behnen P, Dell'Orco D, Koch KW. Involvement of the calcium sensor GCAP1 in hereditary cone dystrophies. Biol Chem. 2010 Jun;391(6):631-7. doi:10.1515/BC.2010.063. Review. PubMed PMID: 20370318.

  • Dell'Orco D, Behnen P, Linse S, Koch KW. Calcium binding, structural stability and guanylate cyclase activation in GCAP1 variants associated with human cone dystrophy. Cell Mol Life Sci. 2010 Mar;67(6):973-84. doi:10.1007/s00018-009-0243-8. PubMed PMID: 20213926.

  • Dell'Orco D, Schmidt H, Mariani S, Fanelli F. Network-level analysis of light adaptation in rod cells under normal and altered conditions. Mol Biosyst. 2009 Oct;5(10):1232-46. doi: 10.1039/b908123b. Epub 2009 Jul 7. PubMed PMID: 19756313.

  • Dell'Orco D. Fast predictions of thermodynamics and kinetics of protein-protein recognition from structures: from molecular design to systems biology. Mol Biosyst. 2009 Apr;5(4):323-34. doi: 10.1039/b821580d. Epub 2009 Feb 19. Review. PubMed PMID: 19396368.

  • Casciari D, Dell'Orco D, Fanelli F. Homodimerization of neurotensin 1 receptor involves helices 1, 2, and 4: insights from quaternary structure predictions and dimerization free energy estimations. J Chem Inf Model. 2008 Aug;48(8):1669-78. doi: 10.1021/ci800048d. Epub 2008 Jul 16. PubMed PMID:18627138.

  • Dell'Orco D, Casciari D, Fanelli F. Quaternary structure predictions and estimation of mutational effects on the free energy of dimerization of the OMPLA protein. J Struct Biol. 2008 Aug;163(2):155-62. doi: 10.1016/j.jsb.2008.05.006. Epub 2008 May 23. PubMed PMID: 18599313.

  • Dell'Orco D, De Benedetti PG. Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases. J Comput Aided Mol Des. 2008 Jun-Jul;22(6-7):469-78. doi: 10.1007/s10822-008-9175-x. Epub 2008 Jan 23. PubMed PMID: 18217217.

  • Dell'Orco D, Schmidt H. Mesoscopic Monte Carlo simulations of stochastic encounters between photoactivated rhodopsin and transducin in disc membranes. J Phys Chem B. 2008 Apr 10;112(14):4419-26. doi: 10.1021/jp709963f. Epub 2008 Mar 18. PubMed PMID: 18345658.

  • Fanelli F, Dell'orco D. Dark and photoactivated rhodopsin share common binding modes to transducin. FEBS Lett. 2008 Mar 19;582(6):991-6. doi: 10.1016/j.febslet.2008.02.041. Epub 2008 Feb 26. PubMed PMID: 18307992.

  • Dell'Orco D, De Benedetti PG, Fanelli F. In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations. J Phys Chem B. 2007 Aug 2;111(30):9114-24. Epub 2007 Jun 28. PubMed PMID: 17602582.

  • Dell'Orco D, De Benedetti PG, Fanelli F. In silico screening of mutational effects on enzyme-proteic inhibitor affinity: a docking-based approach. BMC Struct Biol. 2007 Jun 8;7:37. PubMed PMID: 17559675; PubMed Central PMCID: PMC1913526.

  • Dell'Orco D, Seeber M, Fanelli F. Monomeric dark rhodopsin holds the molecular determinants for transducin recognition: insights from computational analysis. FEBS Lett. 2007 Mar 6;581(5):944-8. Epub 2007 Feb 6. PubMed PMID: 17300784.

  • Fanelli F, Dell'Orco D. Rhodopsin activation follows precoupling with transducin: inferences from computational analysis. Biochemistry. 2005 Nov 15;44(45):14695-700. PubMed PMID: 16274216.

  • Dell'Orco D, Seeber M, De Benedetti PG, Fanelli F. Probing fragment complementation by rigid-body docking: in silico reconstitution of calbindin D9k. J Chem Inf Model. 2005 Sep-Oct;45(5):1429-38. PubMed PMID: 16180920.

  • Dell'Orco D, Xue WF, Thulin E, Linse S. Electrostatic contributions to the kinetics and thermodynamics of protein assembly. Biophys J. 2005 Mar;88(3):1991-2002. Epub 2004 Dec 13. PubMed PMID: 15596501; PubMed Central PMCID: PMC1305251.